M.W. 3148.60 C137H207N41O39S3
somatostatin 28
CAS: 73032-94-7;75037-27-3
Molecular Formula: C137H207N41O39S3
M.W. 3148.60 C137H207N41O39S3 - Names and Identifiers
| Name | somatostatin 28 |
| Synonyms | 28)-disulfide somatostatin 28 Somatostatin 28, Cyclic SOMATOSTATIN 28, CYCLIC M.W. 3148.60 C137H207N41O39S3 Somatostatin-28 (sheep reduced) cyclic (17-28)-disulfide H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys ( Cys17-Cys28) H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bond) SER-ALA-ASN-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS(DISULFIDE BRIDGE CYS17-CYS28) |
| CAS | 73032-94-7 75037-27-3 |
| InChI | InChI=1/C137H207N41O39S3/c1-69(154-113(194)82(37-19-22-47-138)159-115(196)85(40-25-50-149-136(145)146)160-118(199)87(44-45-106(188)189)163-116(197)86(41-26-51-150-137(147)148)164-130(211)101-43-27-52-177(101)133(214)72(4)156-114(195)88(46-54-218-7)158-110(191)71(3)155-129(210)100-42-28-53-178(100)134(215)95(61-104(144)186)171-126(207)96(65-180)172-124(205)93(59-102(142)184)165-111(192)70(2)153-112(193)80(141)64-179)109(190)152-63-105(187)157-98-67-219-220-68-99(135(216)217)174-127(208)97(66-181)173-132(213)108(74(6)183)176-125(206)91(57-77-33-15-10-16-34-77)170-131(212)107(73(5)182)175-119(200)84(39-21-24-49-140)161-122(203)92(58-78-62-151-81-36-18-17-35-79(78)81)168-121(202)90(56-76-31-13-9-14-32-76)166-120(201)89(55-75-29-11-8-12-30-75)167-123(204)94(60-103(143)185)169-117(198)83(162-128(98)209)38-20-23-48-139/h8-18,29-36,62,69-74,80,82-101,107-108,151,179-183H,19-28,37-61,63-68,138-141H2,1-7H3,(H2,142,184)(H2,143,185)(H2,144,186)(H,152,190)(H,153,193)(H,154,194)(H,155,210)(H,156,195)(H,157,187)(H,158,191)(H,159,196)(H,160,199)(H,161,203)(H,162,209)(H,163,197)(H,164,211)(H,165,192)(H,166,201)(H,167,204)(H,168,202)(H,169,198)(H,170,212)(H,171,207)(H,172,205)(H,173,213)(H,174,208)(H,175,200)(H,176,206)(H,188,189)(H,216,217)(H4,145,146,149)(H4,147,148,150) |
M.W. 3148.60 C137H207N41O39S3 - Physico-chemical Properties
| Molecular Formula | C137H207N41O39S3 |
| Molar Mass | 3148.56 |
| Storage Condition | −20°C |
| MDL | MFCD00076772 |
M.W. 3148.60 C137H207N41O39S3 - Risk and Safety
| WGK Germany | 3 |
| RTECS | WF8755700 |
M.W. 3148.60 C137H207N41O39S3 - Introduction
Somatostatin 28(somatostatin 28) is a polypeptide hormone consisting of a chain of 28 amino acids. It is a member of the somatostatin family, mainly in the nervous system and endocrine system.
Somatostatin 28 has a variety of properties and biological activities. It inhibits the secretion of growth hormone and regulates the release of gastric acid secretion, insulin and pancreatic enzymes. It also inhibits gastrointestinal contraction and bile secretion and regulates intestinal absorption and secretion.
Somatostatin 28 is mainly used in the medical field. It can be used to treat diseases such as pheochromocytoma, non-insulin islet cell tumor and carcinoid syndrome. In addition, it can also be used to control the symptoms of hormone excess caused by pituitary tumors or neuroendocrine tumors.
The preparation methods of somatostatin 28 mainly include chemical synthesis and genetic engineering synthesis. Methods of chemical synthesis include polypeptide solid phase methods and liquid phase methods. Genetic engineering techniques Synthesize the gene for somatostatin 28 by expression in bacteria or eukaryotic cells and perform protein purification.
Regarding safety, somatostatin 28 is generally considered safe. However, it must be evaluated and monitored by a doctor before use. Possible side effects include nausea, vomiting, diarrhea, gastrointestinal discomfort, and pain at the injection site. For certain patients, serious side effects such as allergic reactions may occur. Therefore, when using somatostatin 28 should follow the doctor's instructions and comply with the recommendations on dosage and method of use.
Somatostatin 28 has a variety of properties and biological activities. It inhibits the secretion of growth hormone and regulates the release of gastric acid secretion, insulin and pancreatic enzymes. It also inhibits gastrointestinal contraction and bile secretion and regulates intestinal absorption and secretion.
Somatostatin 28 is mainly used in the medical field. It can be used to treat diseases such as pheochromocytoma, non-insulin islet cell tumor and carcinoid syndrome. In addition, it can also be used to control the symptoms of hormone excess caused by pituitary tumors or neuroendocrine tumors.
The preparation methods of somatostatin 28 mainly include chemical synthesis and genetic engineering synthesis. Methods of chemical synthesis include polypeptide solid phase methods and liquid phase methods. Genetic engineering techniques Synthesize the gene for somatostatin 28 by expression in bacteria or eukaryotic cells and perform protein purification.
Regarding safety, somatostatin 28 is generally considered safe. However, it must be evaluated and monitored by a doctor before use. Possible side effects include nausea, vomiting, diarrhea, gastrointestinal discomfort, and pain at the injection site. For certain patients, serious side effects such as allergic reactions may occur. Therefore, when using somatostatin 28 should follow the doctor's instructions and comply with the recommendations on dosage and method of use.
Last Update：2024-04-09 21:51:49
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CAS: 73032-94-7
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CAS: 73032-94-7
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Mobile: 18021002903
QQ: 3008007409
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